The c-kit ligand potentiates the allogeneic mixed lymphocyte reaction

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The c-kit ligand potentiates the allogeneic mixed lymphocyte reaction.

The allogeneic mixed lymphocyte reaction (MLR) is a complex in vitro assay of T-cell recognition and responsiveness in which interleukin-2 (IL-2) plays a central role. We have previously demonstrated that c-kit ligand (KL) can enhance IL-2-induced proliferation in a subset of human natural killer cells expressing the c-kit tyrosine kinase receptor. In the present study, we asked whether KL coul...

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ژورنال

عنوان ژورنال: Blood

سال: 1996

ISSN: 0006-4971,1528-0020

DOI: 10.1182/blood.v88.10.3887.bloodjournal88103887